Methadone - CISMeF

Preferred Label : Methadone;

NCIt synonyms : Methadone Base;

NCIt definition : A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe.;

UNII : UC6VBE7V1Z;

InChIKey : USSIQXCVUWKGNF-UHFFFAOYSA-N;

CAS number : 76-99-3;

Chemical formula : C21H27NO;

ChEBI ID : CHEBI:6807;

Details

Origin ID

C62044;

UMLS CUI

C0025605;

False automatic mappings
- Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified [ICD-10 category (who)]
- Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified [ICD-10 category (who)]
- Methadone [ICD-10 Sub-category (who)]
- Poisoning by, adverse effect of and underdosing of methadone [ICD-10 Sub-category]
See also inter- (CISMeF)
- Methadone metabolite (substance) [SNOMED CT concept]
- Product containing methadone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methadone [ICD-11 Extension code]
- Methadone [LOINC component]
- Methadone (substance) [SNOMED CT concept]
- Product containing methadone (medicinal product) [SNOMED CT concept]
- methadone [ATC Code]
- methadone [Substance BNPC]
- methadone [MeSH Descriptor]
- methadone [SNOMED Notion]
- methadone [MeSH concept]
Validated automatic mappings to BTNT
- methadone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2B6 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Methadone Hydrochloride [NCIt concept]
has_target
- Mu-Type Opioid Receptor [NCIt concept]
is_free_acid_or_base_form_of
- Methadone Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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