Estradiol Acetate

Preferred Label : Estradiol Acetate;

NCIt synonyms : 17Beta-hydroxyestra-1,3,5(10)-trien-3-yl Acetate;

NCIt definition : The acetate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol acetate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.;

UNII : 5R97F5H93P;

InChIKey : FHXBMXJMKMWVRG-SLHNCBLASA-N;

CAS number : 4245-41-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 4245-41-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Femring; Femtrace;

Chemical formula : C20H26O3;

Details

Origin ID

C47990;

UMLS CUI

C1330622;

Automatic exact mappings (from CISMeF team)
- Fertility studies [LOINC component]
- fertility [MeSH Descriptor]
Currated CISMeF NLP mapping
- Estradiol acetate (substance) [SNOMED CT concept]
See also inter- (CISMeF)
- Estradiol acetate preparation (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Estradiol acetate (substance) [SNOMED CT concept]
- Estradiol acetate preparation (product) [Inactive SNOMED CT concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Estradiol [NCIt concept]
is_salt_form_of
- Estradiol [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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