" /> Quinine - CISMeF





Preferred Label : Quinine;

NCIt synonyms : QUIN;

NCIt related terms : (-)-Quinine;

NCIt definition : A quinidine alkaloid isolated from the bark of the cinchona tree. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04);

UNII : A7V27PHC7A;

InChIKey : LOUPRKONTZGTKE-WZBLMQSHSA-N;

CAS number : 130-95-0;

Chemical formula : C20H24N2O2;

NSC code : 192949;

ChEBI ID : CHEBI:15854;

Codes from synonyms : NSC0005362; NSC0192949; 424;

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23/05/2025


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