Lidocaine - CISMeF

Preferred Label : Lidocaine;

NCIt synonyms : 2-Diethylamino-2',6'-acetoxylidide; 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide; Omega-diethylamino-2,6-dimethylacetanilide;

NCIt related terms : .omega.-Diethylamino-2,6-dimethylacetanilide; 2-(Diethylamino)-2',6'-acetoxylidide; Leostesin; Lignocaine; Duncaine; Rucaina;

NCIt definition : A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.;

Alternative definition : NCI-GLOSS: A substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given intravenously to stop heart arrhythmias. It is a type of local anesthetic and antiarrhythmic.;

UNII : 98PI200987;

InChIKey : NNJVILVZKWQKPM-UHFFFAOYSA-N;

CAS number : 137-58-6;

Drug name : Lidothesin; Leostesin; Cuivasil; Duncaine; Rucaina; Lignocaine;

Chemical formula : C14H22N2O;

NSC code : 40030;

ChEBI ID : CHEBI:6456;

Codes from synonyms : NSC0040030; 30126; CDR0000306506;

Details

Origin ID

C614;

UMLS CUI

C0023660;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lidocaine [ICD-11 Extension code]
- Lidocaine [LOINC component]
- Lidocaine (substance) [SNOMED CT concept]
- Product containing lidocaine (medicinal product) [SNOMED CT concept]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [ATC Code]
- lidocaine [Substance BNPC]
- lidocaine [Radlex concept]
- lidocaine [SNOMED Notion]
- lidocaine [MeSH concept]
- lidocaine [MeSH Descriptor]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
chemical_or_drug_metabolism_is_associated_with_allele
- CYP2D6*1 Allele [NCIt concept]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Surgery-Anesthesia Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Lidocaine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Lidocaine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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