Triamcinolone Hexacetonide

Preferred Label : Triamcinolone Hexacetonide;

NCIt synonyms : (11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione;

NCIt definition : The hexacetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone hexacetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.;

UNII : I7GT1U99Y9;

InChIKey : TZIZWYVVGLXXFV-FLRHRWPCSA-N;

CAS number : 5611-51-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5611-51-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Aristospan;

Chemical formula : C30H41FO7;

Details

Origin ID

C48026;

UMLS CUI

C0077004;

Automatic exact mappings (from CISMeF team)
- Triamcinolone hexacetonide [ICHI extension code]
See also inter- (CISMeF)
- Triamcinolone hexacetonide (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Triamcinolone hexacetonide [ICD-11 Extension code]
- Triamcinolone hexacetonide (product) [Inactive SNOMED CT concept]
- Triamcinolone hexacetonide (substance) [SNOMED CT concept]
- triamcinolone hexacetonide [Substance BNPC]
- triamcinolone hexacetonide [MeSH concept]
- triamcinolone hexacetonide [MeSH Supplementary Concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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