Estradiol Hemihydrate

Preferred Label : Estradiol Hemihydrate;

NCIt definition : The hemihydrate form of estradiol, the most potent, naturally produced estrogen. Estradiol hemihydrate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.;

UNII : CXY7B3Q98Z;

InChIKey : ZVVGLAMWAQMPDR-WVEWYJOQSA-N;

CAS number : 35380-71-3;

Drug name : Estrasorb;

Chemical formula : 2C18H24O2.H2O;

Details

Origin ID

C47992;

UMLS CUI

C0772181;

Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Estradiol Hemihydrate [International Nonproprietary Name]
- Estradiol hemihydrate (substance) [SNOMED CT concept]
- Estradiol hemihydrate preparation (product) [Inactive SNOMED CT concept]
- estradiol hemihydrate [MeSH concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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