" /> Domperidone - CISMeF





Preferred Label : Domperidone;

NCIt related terms : Motilium; KW 5338; R 33,812;

NCIt definition : A peripheral-specific antagonist of the dopamine receptor D2 (D2R), with antiemetic, gastrokinetic and galactagogue activities. Following administration, domperidone binds to D2R expressed by peripheral neurons; this inhibits dopamine binding and D2R-mediated signaling. Inhibition of peripheral D2R signaling prevents or relieves various gastrointestinal (GI) symptoms, such as nausea and vomiting, and may help relief reflux and symptoms of a variety of other upper GI disorders.;

UNII : 5587267Z69;

InChIKey : FGXWKSZFVQUSTL-UHFFFAOYSA-N;

CAS number : 57808-66-9;

Drug name : Motilium;

Molecule name : R 33,812; KW 5338;

Chemical formula : C22H24ClN5O2;

NSC code : 299589;

ChEBI ID : CHEBI:31515;

Codes from synonyms : NSC0299589; 167;

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30/07/2025


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