Preferred Label : domperidone;
MeSH definition : A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis,
causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic
mechanisms.;
MeSH synonym : domperidon;
CISMeF synonym : 99497-03-7 (Domperidone maleate); hexal brand of domperidone maleate; stadapharm brand of domperidone maleate; teva brand of domperidone maleate; rottapharm brand of domperidone; taxandria brand of domperidone maleate; janssen brand of domperidone; novopharm brand of domperidone maleate; Nu-Pharm brand of domperidone maleate; nu pharm brand of domperidone maleate; pharmascience brand of domperidone maleate; pierre fabre brand of domperidone; ratiopharm brand of domperidone maleate; apotex brand of domperidone maleate; gry brand of domperidone maleate; aliud brand of domperidone maleate;
DeCS synonym : P ridys;
MeSH hyponym : domidon; domperidona gamir; péridys; Apo-Domperidone; Novo-Domperidone; Domperidone Maleate; R-33,812; ratio-Domperidone; domperidon AL; motilium; Nu-Domperidone; domperidon hexal; nauzelin; domperidone monohydrochloride; domperidone maleate (1:1); PMS-Domperidone; domperidon stada; gastrocure; Domperidon-TEVA; Hexal, Domperidon; Stada, Domperidon; Domperidon TEVA; Gamir, Domperidona; Maleate, Domperidone; Monohydrochloride, Domperidone; Novo Domperidone; Nu Domperidone; PMS Domperidone; R33,812; R-33812; R33812; Ratio Domperidone; Apo Domperidone;
MeSH CAS label : 2H-Benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-;
MeSH Related Number : domperidone maleate; domperidone maleate (1:1); domperidone monohydrochloride; 57808-66-9 (Domperidone); 62781-53-7 (mono-HCl); 83898-65-1 (maleate (1:1)); 99497-03-7 (maleate); 899U5WF46A;
Registry Number MeSH : 57808-66-9;
Related CAS MeSH : 83898-65-1 (Domperidone maleate (1:1)); 62781-53-7 (Domperidone monohydrochloride); 899U5WF46A (Domperidone maleate);
Wikipedia link : https://en.wikipedia.org/wiki/Domperidone;
Codes EINECS : 260-968-7;
Is substance : O;
UNII : 5587267Z69;
InChIKey : FGXWKSZFVQUSTL-UHFFFAOYSA-N;
Origin ID : D004294;
UMLS CUI : C0013015;
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- R 29800 [MeSH Supplementary Concept]
- ovaprim [MeSH Supplementary Concept]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis,
causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic
mechanisms.
https://www.cbip.be/fr/articles/3994?folia=3979
2023
false
false
false
Belgium
French
pharmacovigilance note
journal article
stroke
domperidone
metoclopramide
antiemetics
metopimazine
risk assessment
---
Domperidone and psychiatric withdrawal events when used off-label for lactation stimulation
https://www.canada.ca/fr/sante-canada/services/medicaments-produits-sante/medeffet-canada/infovigilance-produits-sante/aout-2023.html#a3-1-1
2023
false
false
false
Canada
French
English
pharmacovigilance note
domperidone
Off-Label use
substance withdrawal syndrome
Lactation stimulation therapy
---
Domperidone and serious ventricular arrhythmias, QT interval prolongation and sudden
cardiac death
https://www.canada.ca/fr/sante-canada/services/medicaments-produits-sante/medeffet-canada/infovigilance-produits-sante/janvier-2022.html#domperidone
2022
false
false
false
Canada
French
English
journal article
pharmacovigilance note
domperidone
---
https://www.has-sante.fr/portail/jcms/c_2966830/fr/medicaments-antiemetiques-dans-le-traitement-symptomatique-des-nausees-et-vomissements
2019
false
false
false
France
French
nausea
vomiting
antiemetics
domperidone
metoclopramide
metopimazine
metopimazine
domperidone
metoclopramide
child
adult
aged
pregnancy
breast feeding
treatment outcome
drugs, generic
guidelines for drug use
antiemetics
isonipecotic acids
---
https://ansm.sante.fr/uploads/2020/10/30/20201030-dhpc-190628-motilium.pdf
2019
false
false
false
France
French
pharmacovigilance note
guidelines for drug use
risk assessment
domperidone
adult
adolescent
child
domperidone
nausea
vomiting
antiemetics
drug interactions
---
https://www.ansm.sante.fr/actualites/la-domperidone-motilium-et-generiques-ne-doit-plus-etre-utilisee-chez-lenfant-de-moins-de-12-ans
2019
false
false
false
France
French
pharmacovigilance note
guidelines for drug use
torsades de pointes
domperidone
domperidone
antiemetics
antiemetics
drug evaluation
child
adult
domperidone
adolescent
---
https://www.has-sante.fr/portail/jcms/c_2863003/fr/domperidone-mylan
2018
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2757200/fr/domperidone-eg
2017
false
false
false
France
French
evaluation of the transparency committee
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2740898/fr/domperidone-zydus
2017
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2740625/fr/domperidone-biogaran
2017
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2750078/fr/domperidone-almus
2017
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2740892/fr/domperidone-teva
2017
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2729419/fr/domperidone-zentiva
2016
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2658555/fr/domperidone-zentiva
2016
false
false
false
France
French
evaluation of the transparency committee
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2679428/fr/peridys-oroperidys
2016
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
Drug-Induced QT Interval Prolongation in Children: Are the Kids Alright?
http://www.cjhp-online.ca/index.php/cjhp/article/view/1553
http://dx.doi.org/10.4212/cjhp.v69i3.1553
2016
false
false
false
Canadian Journal of Hospital Pharmacy
Canada
French
English
journal article
child
long qt syndrome
Drug-Related side effects and adverse reactions
domperidone
torsades de pointes
gastroesophageal reflux
child, hospitalized
risk factors
continuity of patient care
infant
predisposing factors
causality
---
http://www.has-sante.fr/portail/jcms/c_2627636/fr/domperidone-arrow
http://www.has-sante.fr/portail/jcms/c_2627642/fr/domperidone-zentiva
http://www.has-sante.fr/portail/jcms/c_2627657/fr/domperidone-sandoz
http://www.has-sante.fr/portail/jcms/c_2627660/fr/domperidone-ratiopharm-teva
http://www.has-sante.fr/portail/jcms/c_2627666/fr/domperidone-cristers
http://www.has-sante.fr/portail/jcms/c_2627672/fr/domperidone-biogaran
http://www.has-sante.fr/portail/jcms/c_2627678/fr/domperidone-mylan
http://www.has-sante.fr/portail/jcms/c_2627684/fr/domperidone-eg
2016
false
false
false
France
French
evaluation of the transparency committee
adult
child
administration, oral
domperidone
treatment outcome
antiemetics
domperidone
insurance, health, reimbursement
domperidone
antiemetics
cardiovascular diseases
drugs, generic
---
http://www.has-sante.fr/portail/jcms/c_2676750/fr/domperidone-mylan
2016
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
http://www.has-sante.fr/portail/jcms/c_2729437/fr/domperidone-sandoz
2016
false
false
false
France
French
evaluation of the transparency committee
domperidone
domperidone
---
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/43423a-fra.php
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/43449a-fra.php
2015
false
false
false
Canada
French
English
Domperidone Maleate
domperidone
pharmacovigilance note
patient education handout
arrhythmias, cardiac
death, sudden, cardiac
antiemetics
dopamine antagonists
Ventricular Arrhythmia
adult
aged
risk factors
Domperidone Maleate
dopamine antagonists
antiemetics
Cardiotoxicity
Contraindications, Procedure
domperidone
domperidone
Contraindications, Drug
---
https://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/domperidone-fra.php
2015
false
false
false
Canada
French
pharmacovigilance note
domperidone
domperidone
death, sudden, cardiac
antiemetics
administration, oral
long qt syndrome
arrhythmias, cardiac
canada
risk factors
risk
drug evaluation
risk assessment
Cardiotoxicity
---
Chez l’enfant, intérêt clinique insuffisant en raison d’une efficacité non démontrée.
Chez l’adulte, intérêt clinique faible en raison d’une efficacité mal établie à la
posologie désormais recommandée pour réduire le risque de survenue d’effets indésirables
cardiaques graves
http://www.has-sante.fr/portail/jcms/c_2053548/fr/motilium
http://www.has-sante.fr/portail/jcms/c_2053548/fr/specialites-a-base-de-domperidone-stimulant-de-la-motricite-intestinale-motilium
2015
false
false
false
France
French
evaluation of the transparency committee
adult
child
administration, oral
domperidone
treatment outcome
antiemetics
domperidone
insurance, health, reimbursement
domperidone
antiemetics
cardiovascular diseases
guidelines for drug use
---
Chez l’enfant, intérêt clinique insuffisant en raison d’une efficacité non démontrée.
Chez l’adulte, intérêt clinique faible en raison d’une efficacité mal établie à la
posologie désormais recommandée pour réduire le risque de survenue d’effets indésirables
cardiaques graves
http://www.has-sante.fr/portail/jcms/c_2055733/fr/peridys-oroperidys
http://www.has-sante.fr/portail/jcms/c_2055733/fr/specialites-a-base-de-domperidone-stimulant-de-la-motricite-intestinale-peridys-oroperidys
2015
false
false
false
France
French
evaluation of the transparency committee
adult
child
administration, oral
domperidone
treatment outcome
antiemetics
domperidone
insurance, health, reimbursement
domperidone
antiemetics
cardiovascular diseases
guidelines for drug use
---
http://www.lecrat.eu/?s=Domp%C3%A9ridone
2014
France
French
pregnancy
domperidone
antiemetics
dopamine antagonists
domperidone
drug information
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61139203
2013
summary of product characteristics
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67116396
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66152959
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62128302
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63907947
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65065017
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61118045
2012
France
summary of product characteristics
package leaflet
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64230487
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68054595
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62417552
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66585953
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60639091
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69916757
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63230000
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65601290
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66456848
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60548282
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66398576
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69139269
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65938724
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60764337
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63394334
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63333858
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68427304
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64930137
2012
France
summary of product characteristics
package leaflet
suspensions
domperidone
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67423356
2012
France
summary of product characteristics
package leaflet
tablets
domperidone
---
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/14118a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/15857a-fra.php
2012
Canada
French
English
Cardiotoxicity
domperidone
death, sudden, cardiac
antiemetics
domperidone
adult
aged
administration, oral
Domperidone Maleate
dopamine antagonists
arrhythmias, cardiac
pharmacovigilance note
patient education handout
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63630635
2012
France
summary of product characteristics
package leaflet
domperidone
tablets
---
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Domperidone.aspx
2009
Canada
popular works
drug information
child
domperidone
---
http://www.has-sante.fr/portail/display.jsp?id=c_400244
2005
France
evaluation of the transparency committee
domperidone
---
http://www.has-sante.fr/portail/display.jsp?id=c_400235
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct031810.pdf
2005
France
French
administration, oral
domperidone
domperidone
antiemetics
adult
adolescent
evaluation of the transparency committee
---