Polyestradiol Phosphate

Preferred Label : Polyestradiol Phosphate;

NCIt synonyms : Estradiol Phosphate Polymer; PEP;

NCIt definition : A synthetic long-acting polymer derivative of the female sex hormone estradiol. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Administration of polyestradiol phosphate leads to the marked decrease of testosterone levels and may exhibit a bone mass-preserving effect in patients with prostatic cancer. (NCI04);

UNII : P14877CDX2;

CAS number : 28014-46-2; 9009-22-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 28014-46-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 9009-22-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Estradurin;

Molecule name : Leo 114;

NCI Metathesaurus CUI : CL557928;

Details

Origin ID

C1199;

UMLS CUI

C0071554;

Currated CISMeF NLP mapping
- Polyestradiol phosphate [ICD-11 Extension code]
- Polyestradiol phosphate (substance) [SNOMED CT concept]
- Product containing polyestradiol phosphate (medicinal product) [SNOMED CT concept]
- polyestradiol phosphate [MeSH concept]
- polyestradiol phosphate [MeSH Supplementary Concept]
- polyestradiol phosphate [SNOMED Notion]
False automatic mappings
- Epilepsy, partial, with pericentral spikes [OMIM Phenotype]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Polyestradiol phosphate [ICD-11 Extension code]
- Polyestradiol phosphate (substance) [SNOMED CT concept]
- Product containing polyestradiol phosphate (medicinal product) [SNOMED CT concept]
- polyestradiol phosphate [ATC Code]
- polyestradiol phosphate [SNOMED Notion]
- polyestradiol phosphate [MeSH Supplementary Concept]
- polyestradiol phosphate [MeSH concept]
Validated automatic mappings to BTNT
- polyestradiol phosphate [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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