" /> Haloperidol - CISMeF





Preferred Label : Haloperidol;

NCIt synonyms : 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone;

NCIt related terms : McN-JR-1625; Haldol; R-1625; R 1625;

NCIt definition : A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity.;

Alternative definition : NCI-GLOSS: A drug used to treat certain mental and neurological disorders. It is also being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of antiemetic and a type of antipsychotic.;

UNII : J6292F8L3D;

InChIKey : LNEPOXFFQSENCJ-UHFFFAOYSA-N;

CAS number : 52-86-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 52-86-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Haldol;

Molecule name : McN-JR-1625; R-1625;

Chemical formula : C21H23ClFNO2;

NSC code : 170973;

ChEBI ID : CHEBI:5613;

Codes from synonyms : CDR0000572159; NSC0615296; NSC0170973; 00482; CDR0000476306; 253;

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06/05/2024


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