NCIt related terms : McN-JR-1625; Haldol; R-1625; R 1625;
NCIt definition : A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic
activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors
in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission
and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity
mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts
for its antiemetic activity.;
Alternative definition : NCI-GLOSS: A drug used to treat certain mental and neurological disorders. It is also
being studied in the treatment of nausea and vomiting caused by some cancer treatments.
It is a type of antiemetic and a type of antipsychotic.;
UNII : J6292F8L3D;
InChIKey : LNEPOXFFQSENCJ-UHFFFAOYSA-N;
CAS number : 52-86-8;
Drug name : Haldol;
Molecule name : McN-JR-1625; R-1625;
Chemical formula : C21H23ClFNO2;
NSC code : 170973;
ChEBI ID : CHEBI:5613;
Codes from synonyms : CDR0000572159; NSC0615296; NSC0170973; 00482; CDR0000476306; 253;
https://www.cochrane.org/fr/CD013425/SCHIZ_lhaloperidol-compare-lolanzapine-chez-les-personnes-atteintes-de-schizophrenie 2024 United Kingdom review of literature french abstract Haloperidol Comparison Schizophrenia persons People schizophrenia Olanzapine Measurement Olanzapine Olanzapine haloperidol schizophrenia haloperidol disease schizophrenia, nos