" /> Prednisolone Acetate - CISMeF





Preferred Label : Prednisolone Acetate;

NCIt related terms : Econopred; Pred Mild; Pred Forte;

NCIt definition : The acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. As a glucocorticoid receptor agonist, prednisolone acetate binds to specific intracellular glucocorticoid receptors, and causes the ligand-receptor complex to be translocated to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.;

UNII : 8B2807733D;

InChIKey : LRJOMUJRLNCICJ-JZYPGELDSA-N;

CAS number : 52-21-1;

Drug name : Predaject; Locaseptil-Neo; Deltacortilen; Ak-Tate; Predni-H; Balpred; Deltastab; Hydrocortancyl; Hexacortone; Predalone; Diopred; Pred Fort; Predcor; Econopred; Predniocil; Di-Adreson-F; Key-Pred; Articulose-50; Pred Forte; Predate; Prednefrin SF; Inf-Oph; Ophtho-Tate; Prednihexal; Predni-POS; Inflanefran; Pred Mild; Flo-Pred;

Chemical formula : C23H30O6;

NSC code : 10966;

Codes from synonyms : NSC0010966;

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Keyword's position in hierarchy(ies) : arborescence

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22/05/2025


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