" /> Midazolam Hydrochloride - CISMeF





Preferred Label : Midazolam Hydrochloride;

NCIt synonyms : 8-Chloro-6-(2-fluorophenyl)-1-Methyl- 4H- Imidazo(1,5a)(1,4)Benzodiazepine;

NCIt related terms : midazolam; Versed;

NCIt definition : The hydrochloride salt of a short-acting benzodiazepine derivative with an imidazole structure and anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties. Midazolam binds to the benzodiazepine receptor at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS), resulting in increases in the opening of chloride channels, membrane hyperpolarization, and the inhibitory effect of GABA. This agent may also interfere with the reuptake of GABA, thereby causing accumulation of GABA in the synaptic cleft.;

Alternative definition : NCI-GLOSS: A drug used to treat anxiety and tension and to relax muscles. It is also being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of benzodiazepine.;

UNII : W7TTW573JJ;

InChIKey : PLYSCVSCYOQVRP-UHFFFAOYSA-N;

CAS number : 59467-96-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 59467-96-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Versed;

Chemical formula : C18H13ClFN3.HCl;

Codes from synonyms : CDR0000572162; CDR0000572161; CDR0000476308;

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05/05/2024


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