Delavirdine Mesylate

Preferred Label : Delavirdine Mesylate;

NCIt synonyms : Delavirdine Monomethanesulfonate; Piperazine, 1-(3-((1-Methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)-, Monomethanesulfonate;

NCIt definition : A mesylate salt form of delavirdine, a synthetic, non-nucleoside reverse transcriptase inhibitor. In combination with other anti-retroviral drugs, this agent has been shown to reduce HIV viral load and increase CD4 leukocyte counts in patients. As an inhibitor of the cytochrome P450 system, delavirdine may result in increased serum levels of co-administered protease inhibitors metabolized by the cytochrome P450 system.;

UNII : 421105KRQE;

InChIKey : MEPNHSOMXMALDZ-UHFFFAOYSA-N;

CAS number : 147221-93-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 147221-93-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Rescriptor;

Molecule name : U-90; U-90152; U 90152;

Chemical formula : C22H28N6O3S.CH4O3S;

ChEBI ID : CHEBI:4379;

Details

Origin ID

C28974;

UMLS CUI

C0543492;

Currated CISMeF NLP mapping
- Delavirdine mesilate (substance) [SNOMED CT concept]
- delavirdine mesylate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Delavirdine mesilate (substance) [SNOMED CT concept]
- delavirdine mesylate [MeSH concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Delavirdine [NCIt concept]
is_salt_form_of
- Delavirdine [NCIt concept]

Keyword's position in hierarchy(ies) :

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