Preferred Label : Halcinonide;
NCIt synonyms : Volog; Halcort; Halciderm; 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal
with Acetone; Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-,(11beta,16alpha)-;
NCIt definition : A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties.
Halcinonide exerts its effect by interacting with specific intracellular receptors,
and the ligand-receptor complex subsequently modulates gene expressions via the typical
glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory
proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently,
an overall reduction in chronic inflammation and autoimmune reactions are accomplished.
(NCI05);
UNII : SI86V6QNEG;
InChIKey : MUQNGPZZQDCDFT-JNQJZLCISA-N;
CAS number : 3093-35-4;
Drug name : Halog;
Chemical formula : C24H32ClFO5;
Origin ID : C47552;
UMLS CUI : C0018513;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset
