Preferred Label : Gentamicin Sulfate/Betamethasone Valerate/Clotrimazole Otic Ointment;
NCIt synonyms : Gentamicin/Betamethasone/Clotrimazole Otic Ointment;
NCIt definition : An otic ointment formulation of the broad-spectrum aminoglycoside antibiotic gentamicin
sulfate, the synthetic adrenocorticoid betamethasone valerate and the broad-spectrum
antifungal agent clotrimazole, with antibacterial, anti-inflammatory, and antifungal
activities. Upon otic administration, gentamicin sulfate/betamethasone valerate/clotrimazole
otic ointment inhibits bacterial protein synthesis and replication, inhibits fungal
sterols biosynthesis which leads to fungal cell leakage and fungal cell lysis, and
inhibits the inflammatory response by preventing phospholipid release, inhibiting
eosinophil activity, and decreasing pro-inflammatory cytokine production.;
Drug name : Otomax;
NCI Metathesaurus CUI : CL1413021;
Origin ID : C175558;
UMLS CUI : C5446620;
Semantic type(s)
- chemical_or_drug_is_metabolized_by_enzyme
