Preferred Label : Methylprednisolone;
NCIt synonyms : 6Alpha-Methylprednisolone; (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione; Methylprednisolonum;
NCIt related terms : Medrone; Urbason; Medrate; Medrol; Wyacort;
NCIt definition : A synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
Methylprednisolone binds to and activates specific nuclear receptors, resulting in
altered gene expression and inhibition of proinflammatory cytokine production. This
agent also decreases the number of circulating lymphocytes, induces cell differentiation,
and stimulates apoptosis in sensitive tumor cell populations.;
Alternative definition : NCI-GLOSS: A corticosteroid hormone replacement.;
UNII : X4W7ZR7023;
InChIKey : VHRSUDSXCMQTMA-PJHHCJLFSA-N;
CAS number : 83-43-2;
Drug name : Duralone; Depo Moderin; Solpredone; Metypresol; Caberdelta M; Prednilen; Summicort; Firmacort; Metysolon; Medlone 21; Medrone; Metrocort; Sieropresol; Adlone; Emmetipi; Medrol; Meprolone; DepMedalone; Esametone; Metilbetasone Solubile; Veriderm Medrol; Mega-Star; Depo-Nisolone; Urbason; Predni-M-Tablinen; Radilem; Wyacort;
Chemical formula : C22H30O5;
NSC code : 19987;
ChEBI ID : CHEBI:6888;
Codes from synonyms : NSC0019987; 00191; CDR0000045370; 331;
Origin ID : C647;
UMLS CUI : C0025815;
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
chemical_or_drug_is_metabolized_by_enzyme
concept_is_in_subset
has_salt_form
has_target
is_component_of_chemotherapy_regimen
is_free_acid_or_base_form_of
https://www.has-sante.fr/jcms/p_3487178/fr/solu-medrol-methylprednisolone-corticoides
2024
false
false
false
France
injections, intravenous
injections, intramuscular
evaluation of the transparency committee
adrenal cortical hormone, nos
corticoids
methylprednisolone hemisuccinate
medrol
Methylprednisolone
glucocorticoids
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