" /> Astemizole - CISMeF





Preferred Label : Astemizole;

NCIt synonyms : 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)eth l)-4-piperidinyl)-; 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole;

NCIt definition : A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04);

UNII : 7HU6337315;

InChIKey : GXDALQBWZGODGZ-UHFFFAOYSA-N;

CAS number : 68844-77-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 68844-77-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Hismanal; Paralergin; Retolen;

Molecule name : R 42512; R 43,512;

Chemical formula : C28H31FN4O;

ChEBI ID : CHEBI:2896;

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11/05/2024


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