Astemizole - CISMeF

Preferred Label : Astemizole;

NCIt synonyms : 1H-Benzimidazol-2-amine, 1-((4-fluorophenyl)methyl)-N-(1-(2-(4-methoxyphenyl)eth l)-4-piperidinyl)-; 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole;

NCIt definition : A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04);

UNII : 7HU6337315;

InChIKey : GXDALQBWZGODGZ-UHFFFAOYSA-N;

CAS number : 68844-77-9;

Drug name : Hismanal; Paralergin; Retolen;

Molecule name : R 42512; R 43,512;

Chemical formula : C28H31FN4O;

ChEBI ID : CHEBI:2896;

Details

Origin ID

C28834;

UMLS CUI

C0085170;

Currated CISMeF NLP mapping
- Astemizole [ICD-11 Extension code]
- Astemizole [ICHI extension code]
- Astemizole [LOINC component]
- Astemizole (substance) [SNOMED CT concept]
- astemizole [Substance BNPC]
- astemizole [MeSH Descriptor]
- astemizole [MeSH concept]
- astemizole [SNOMED Notion]
False automatic mappings
- Product containing astemizole (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Astemizole [ICD-11 Extension code]
- Astemizole [LOINC component]
- Astemizole (substance) [SNOMED CT concept]
- Product containing astemizole (medicinal product) [SNOMED CT concept]
- astemizole [ATC Code]
- astemizole [Substance BNPC]
- astemizole [MeSH concept]
- astemizole [SNOMED Notion]
- astemizole [MeSH Descriptor]
Validated automatic mappings to BTNT
- astemizole [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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