Dextromethorphan

Preferred Label : Dextromethorphan;

NCIt synonyms : DXM; Dextromethorphan Base;

NCIt definition : A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.;

UNII : 7355X3ROTS;

InChIKey : MKXZASYAUGDDCJ-NJAFHUGGSA-N;

CAS number : 125-71-3;

Chemical formula : C18H25NO;

ChEBI ID : CHEBI:4470;

Details

Origin ID

C62022;

UMLS CUI

C0011816;

Currated CISMeF NLP mapping
- Dextromethorphan [ICD-11 Extension code]
- Dextromethorphan [ICHI extension code]
- Dextromethorphan [SMS substance]
- Dextromethorphan [LOINC component]
- Dextromethorphan (substance) [SNOMED CT concept]
- dextromethorphan [International Nonproprietary Name]
- dextromethorphan [Substance BNPC]
- dextromethorphan [MeSH Descriptor]
- dextromethorphan [MeSH concept]
- dextromethorphan [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dextromethorphan [ICD-11 Extension code]
- Dextromethorphan [LOINC component]
- Dextromethorphan (substance) [SNOMED CT concept]
- Product containing dextromethorphan (medicinal product) [SNOMED CT concept]
- dextromethorphan [ATC Code]
- dextromethorphan [Substance BNPC]
- dextromethorphan [International Nonproprietary Name]
- dextromethorphan [SNOMED Notion]
- dextromethorphan [MeSH Descriptor]
- dextromethorphan [MeSH concept]
Validated automatic mappings to BTNT
- dextromethorphan [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Dextromethorphan Hydrobromide [NCIt concept]
is_free_acid_or_base_form_of
- Dextromethorphan Hydrobromide [NCIt concept]

Keyword's position in hierarchy(ies) :

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