Dextromethorphan Hydrobromide

Preferred Label : Dextromethorphan Hydrobromide;

NCIt synonyms : Dextromethorphan;

NCIt definition : The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.;

UNII : 9D2RTI9KYH;

InChIKey : STTADZBLEUMJRG-IKNOHUQMSA-N;

CAS number : 6700-34-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 6700-34-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C18H25NO.BrH.H2O;

Details

Origin ID

C423;

UMLS CUI

C0350422;

Automatic exact mappings (from CISMeF team)
- Dextromethorphan [ICHI extension code]
See also inter- (CISMeF)
- Dextromethorphan hydrobromide (product) [Inactive SNOMED CT concept]
- Product containing dextromethorphan (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Dextromethorphan [LOINC component]
- Dextromethorphan [ICD-11 Extension code]
- Dextromethorphan (substance) [SNOMED CT concept]
- dextromethorphan [MeSH Descriptor]
- dextromethorphan [International Nonproprietary Name]
- dextromethorphan [Substance BNPC]
- dextromethorphan [MeSH concept]
- dextromethorphan [ATC Code]
- dextromethorphan [SNOMED Notion]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Dextromethorphan [NCIt concept]
is_component_of_chemotherapy_regimen
- Dextromethorphan/Morphine [NCIt concept]
is_salt_form_of
- Dextromethorphan [NCIt concept]

Keyword's position in hierarchy(ies) :

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