NCIt definition : A cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds
to and activates muscarinic receptors, thereby increasing the secretions in exocrine
salivary and sweat glands. This cholinergic agonist also increases the tone of smooth
muscle in the gastrointestinal and urinary tracts. Cevimeline is being studied as
a treatment for dry mouth caused by radiation therapy to the head and neck.;
Alternative definition : NCI-GLOSS: A drug used to treat certain disorders of the salivary gland. It is also
being studied as a treatment for dry mouth caused by radiation therapy to the head
and neck. It increases the amount of saliva and sweat made by saliva and sweat glands.
Cevimeline hydrochloride is a type of cholinergic agonist.;
UNII : P81Q6V85NP;
InChIKey : ZSTLCHCDLIUXJE-ZGBAEQJLSA-N;
CAS number : 153504-70-2;
Drug name : Evoxac;
Molecule name : AF-102B;
Chemical formula : 2C10H17NOS.2HCl.H2O;
Codes from synonyms : CDR0000633702; CDR0000633304;