NCIt definition : A cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds
to and activates muscarinic receptors, thereby increasing the secretions in exocrine
salivary and sweat glands. This cholinergic agonist also increases the tone of smooth
muscle in the gastrointestinal and urinary tracts. Cevimeline is being studied as
a treatment for dry mouth caused by radiation therapy to the head and neck.;
Alternative definition : NCI-GLOSS: A substance that increases production of saliva and tears. It is being
studied as a treatment for dry mouth caused by radiation therapy to the head and neck.
It belongs to the family of drugs called cholinergic enhancers.;