" /> Enalapril Maleate - CISMeF





Preferred Label : Enalapril Maleate;

NCIt synonyms : Enalapril;

NCIt definition : The maleate salt form of enalapril, a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 9O25354EPJ;

InChIKey : OYFJQPXVCSSHAI-QFPUQLAESA-N;

CAS number : 76095-16-4;

Drug name : Renitec; Vasotec; Enacard;

Chemical formula : C20H28N2O5.C4H4O4;

ChEBI ID : CHEBI:4785;

Codes from synonyms : 32060;

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08/05/2025


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