" /> Hydrocortisone Sodium Succinate - CISMeF





Preferred Label : Hydrocortisone Sodium Succinate;

NCIt synonyms : Hydrocortisone 21-Sodium Succinate; Hycorace; Cortisol Sodium Succinate; (11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt; Hydrocortisone Na Succinate;

NCIt related terms : Corlan; Hydro-adreson; Flebocortid; Buccalsone; Nordicort; Sodium hydrocortisone succinate; Solu-Cortef; Solu-Glyc;

NCIt definition : The sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibiting minor mineralocorticoid effects. This agent binds to intracellular glucocorticoid receptors and is translocated into the nucleus, where it initiates the transcription of glucocorticoid-responsive genes, such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation.;

UNII : 50LQB69S1Z;

InChIKey : HHZQLQREDATOBM-CODXZCKSSA-M;

CAS number : 125-04-2;

Drug name : Emergent-EZ; Efcortelan; Buccalsone; Hidroc Clora; A-Hydrocort; Sinsurrene; Corlan; Solu-Glyc; Nordicort; Hydro-Adreson; Hydrocort; Solu-Cortef; Flebocortid; Kinogen; Cortop; Nositrol;

Chemical formula : C25H33O8.Na;

NSC code : 9152;

Codes from synonyms : 06055; NSC0010483; NSC0009152;

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02/05/2025


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