Preferred Label : Cyclophosphamide;
NCIt synonyms : Ciclofosfamide; 2-[di(chloroethyl)amino]-1-oxa-3-aza-2-phosphacyclohexane 2-oxide monohydrate; Cyclophosphamid monohydrate; N,N-bis(b-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate; Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate; N,N-bis(beta-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate; N,N-bis(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate; Mitoxan; 2-[bis(b-chloroethyl)amino]-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydrate; N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide monohydrate; Cyclophospham; bis(2-chloroethyl)phosphamide cyclic propanolamide ester monohydrate; Claphene; N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)phosphorodiamidic acid intramolecular ester
monohydrate; 1-bis(2-chloroethyl)-amino-1-oxo-2-aza-5-oxaphosphoridin monohydrate; Cyclophosphanum; Cytophosphane; 2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate; N,N-bis(beta-chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate; Syklofosfamid; Ciclofosfamida; CP monohydrate; Revimmune; Neosar; Cyclophosphamide Monohydrate;
NCIt related terms : (-)-Cyclophosphamide; 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate; Cyclophosphane; Cyclostin; CTX; Clafen; Genoxal; Cytophosphan; Cyclophosphan; Cyclophosphamidum; Cytoxan;
NCIt definition : A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic
and immunosuppressive activities. In the liver, cyclophosphamide is converted to the
active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby
inhibiting DNA replication and initiating cell death.;
Alternative definition : NCI-GLOSS: A drug that is used to treat many types of cancer and is being studied
in the treatment of other types of cancer. It is also used to treat some types of
kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill
cancer cells. It is a type of alkylating agent.;
UNII : 8N3DW7272P;
InChIKey : PWOQRKCAHTVFLB-UHFFFAOYSA-N;
CAS number : 6055-19-2;
Drug name : Carloxan; Cyclostin; Ledoxina; Cicloxal; Cycloblastin; Genoxal; Genuxal; Fosfaseron; Cytophosphan; Cyclostine; Cycloblastine; CYCLO-cell;
Molecule name : WR- 138719; WR-138719; Asta B 518; B-518; B 518;
Chemical formula : C7H15Cl2N2O2P.H2O;
NSC code : 26271;
ChEBI ID : CHEBI:4026;
Codes from synonyms : CDR0000045253; 01333; CDR0000635729; CDR0000635728; NSC0026271; 122;
Origin ID : C405;
UMLS CUI : C0010583;
False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
https://www.rheuma-net.ch/fr/doc/cyclophosphamid-1/viewdocument/348
2024
Switzerland
guideline
cyclophosphamide
cyclophosphamide
Background Treatment
Cyclophosphamide
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