Therapeutic Progesterone

Preferred Label : Therapeutic Progesterone;

NCIt synonyms : 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; Delta4-pregnene-3,20-dione;

NCIt related terms : Corluvite; Proluton; Syngesterone; Corlutina; Lutromone; Utrogestan; Prolidon; Lutogyl; Progestin; Progestasert; Corpus luteum hormone; Lipo-Lutin; Cyclogest; Lutocyclin; Gestone; PROGESTERONE; Luteohormone;

NCIt definition : The therapeutic form of the naturally occurring hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy.;

UNII : 4G7DS2Q64Y;

InChIKey : RJKFOVLPORLFTN-LEKSSAKUSA-N;

CAS number : 57-83-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 57-83-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Progestol; Lutromone; Corlutina; Proluton; Syngesterone; Luteohormone; Lipo-Lutin; Lutocylin M; Corluvite; Gestone; Prolidon; Cyclogest; Lutocyclin; Progeston; Gestiron; Progestogel; Utrogestan; Progestasert; Lutogyl;

Chemical formula : C21H30O2;

NSC code : 64377; 9704;

ChEBI ID : CHEBI:17026; CHEBI:59826;

Codes from synonyms : NSC0009704; 00451;

Details

Origin ID

C777;

UMLS CUI

C0033308;

Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing progesterone (medicinal product) [SNOMED CT concept]
- Progesterone [LOINC component]
- Progesterone (substance) [SNOMED CT concept]
- progesterone [ATC Code]
- progesterone [SNOMED Notion]
- progesterone [MeSH Descriptor]
- progesterone [MeSH concept]
- progesterone deficiency [Disease (Nov.)]
- progesterone preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- progesterone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
is_related_to_endogenous_product
- Progesterone [NCIt concept]

Keyword's position in hierarchy(ies) :

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