NCIt definition : The 17-valerate ester of betamethasone, a synthetic glucocorticoid with metabolic,
immunosuppressive and anti-inflammatory actions. Betamethasone valerate binds to specific
intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene
expression. The synthesis of certain anti-inflammatory proteins is induced while the
synthesis of certain inflammatory mediators is inhibited. As a result, there is an
overall reduction in chronic inflammation and autoimmune reactions.;