Preferred Label : Dexamethasone Intravitreal Implant;
NCIt definition : An intravitreal implant containing the corticosteroid dexamethasone embedded in a
biodegradable polymer matrix, with anti-inflammatory and macular edema relieving activity.
Upon insertion into the vitreous cavity, dexamethasone intravitreal implant is dissolved
slowly and dexamethasone is released over an extended period of time. Dexamethasone
inhibits inflammation thereby preventing leakage from the capillaries and a reduction
of retinal edema. This may ultimately prevent vision impairment.;
Drug name : Ozurdex;
Origin ID : C99171;
UMLS CUI : C2702454;
Semantic type(s)
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset
https://www.ansm.sante.fr/S-informer/Informations-de-securite-Lettres-aux-professionnels-de-sante/Ozurdex-R-700-microgrammes-implant-intravitreen-avec-applicateur-dexamethasone-recommandations-suite-a-la-detection-de-particule-de-silicone-sur-certains-implants-Lettre-aux-professionnels-de-sante
2018
false
false
false
France
French
drug implants
pharmacovigilance note
drug contamination
watchful waiting
Safety-Based drug withdrawals
guidelines for drug use
dexamethasone
Dexamethasone Intravitreal Implant
intravitreal injections
risk assessment
silicones
ocular inflammation
eye diseases
silicones
dexamethasone
---
http://www.has-sante.fr/portail/jcms/c_2625992/fr/ozurdex
2016
false
France
French
Adrenocortical steroid therapy
Glucocorticoid therapy
corticosteroid therapy
evaluation of the transparency committee
Dexamethasone Intravitreal Implant
macular edema
drug implants
absorbable implants
dexamethasone
Delayed-Action preparations
glucocorticoids
uveitis
treatment outcome
Intravitreal implant (physical object)
Non-infectious posterior uveitis
---
