Nicardipine Hydrochloride

Preferred Label : Nicardipine Hydrochloride;

NCIt synonyms : Nicardipine;

NCIt definition : The hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator. (NCI04);

UNII : K5BC5011K3;

InChIKey : AIKVCUNQWYTVTO-UHFFFAOYSA-N;

CAS number : 54527-84-3;

Chemical formula : C26H29N3O6.HCl;

Codes from synonyms : 9315;

Details

Origin ID

C29840;

UMLS CUI

C0770150;

Automatic exact mappings (from CISMeF team)
- Nicardipine [ICHI extension code]
- Product containing nicardipine (medicinal product) [SNOMED CT concept]
- nicardipine [ATC Code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Nicardipine [ICD-11 Extension code]
- Nicardipine [SMS substance]
- Nicardipine (substance) [SNOMED CT concept]
- niCARdipine [LOINC component]
- nicardipine [MeSH concept]
- nicardipine [MeSH Descriptor]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Nicardipine [NCIt concept]
is_salt_form_of
- Nicardipine [NCIt concept]

Keyword's position in hierarchy(ies) :

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