Flunisolide - CISMeF

Preferred Label : Flunisolide;

NCIt definition : A synthetic corticosteroid with antiinflammatory and antiallergic properties. Flunisolide is a glucocorticoid receptor agonist that binds to cytoplasmic glucocorticoid receptors and subsequently translocates to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both are potent mediators of inflammation.;

UNII : QK4DYS664X;

InChIKey : MIXMJCQRHVAJIO-TZHJZOAOSA-N;

CAS number : 77326-96-6;

Chemical formula : 2C24H31FO6.H2O;

Details

Origin ID

C29054;

UMLS CUI

C0060501;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Flunisolide [ICD-11 Extension code]
- Flunisolide [LOINC component]
- Flunisolide (substance) [SNOMED CT concept]
- Product containing flunisolide (medicinal product) [SNOMED CT concept]
- flunisolide [ATC Code]
- flunisolide [ATC Code]
- flunisolide [Substance BNPC]
- flunisolide [MeSH concept]
- flunisolide [MeSH Supplementary Concept]
- flunisolide preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- flunisolide [ATC Code]
- flunisolide [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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