Alfentanil Hydrochloride

Preferred Label : Alfentanil Hydrochloride;

NCIt definition : The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.;

UNII : 11S92G0TIW;

InChIKey : YYESXRRYBUERKF-UHFFFAOYSA-N;

CAS number : 70879-28-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 70879-28-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Rapifen; Alfenta;

Chemical formula : C21H32N6O3.ClH.H2O;

Details

Origin ID

C220;

UMLS CUI

C0700562;

Automatic exact mappings (from CISMeF team)
- alfentanil [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- alfentanil [MeSH Descriptor]
- alfentanil [Substance BNPC]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Alfentanil [NCIt concept]
is_salt_form_of
- Alfentanil [NCIt concept]

Keyword's position in hierarchy(ies) :

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