Therapeutic Estradiol

Preferred Label : Therapeutic Estradiol;

NCIt synonyms : 17 Beta-Estradiol; (17beta)-Estra-1,3,5(10)-triene-3,17-diol;

NCIt related terms : Diogyn; Dimenformon; Aquadiol; Estrace; ESTRADIOL; Progynon; Estraldine; Oestradiol; Ovocylin; Diogynets;

NCIt definition : A synthetic form of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females, that may be used as hormone replacement therapy. Typically esterified, estradiol derivatives are formulated for oral, intravaginal, transdermal, or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. It may play a role in immune and inflammatory processes.;

UNII : 4TI98Z838E;

InChIKey : VOXZDWNPVJITMN-ZBRFXRBCSA-N;

CAS number : 50-28-2;

Drug name : Aquadiol; Diogyn; Diogynets; Progynon; Ovocylin; Estrace; Dimenformon; Vagifem; Climara;

Chemical formula : C18H24O2;

NSC code : 9895; 20293;

ChEBI ID : CHEBI:16469;

Codes from synonyms : NSC0009895;

Détails

Origin ID

C478;

UMLS CUI

C4721525;

Automatic exact mappings (from CISMeF team)
- Product containing estradiol (medicinal product) [SNOMED CT concept]
- estradiol [ATC Code]
- mosquito nets [MeSH Descriptor]
Currated CISMeF NLP mapping
- Estradiol [MedDRA LLT]
- Estradiol [LOINC component]
- Estradiol (substance) [SNOMED CT concept]
- Oestradiol [MedDRA Preferred Term]
- betaestradiol 17-(beta-D-glucuronide) [MeSH concept]
- estradiol [SNOMED Notion]
- estradiol [EMDN type]
- estradiol [MeSH Descriptor]
- estradiol [MeSH concept]
- estradiol [Substance BNPC]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Estradiol [LOINC component]
- Estradiol (substance) [SNOMED CT concept]
- Product containing estradiol (medicinal product) [SNOMED CT concept]
- estradiol [ATC Code]
- estradiol [MeSH concept]
- estradiol [SNOMED Notion]
- estradiol [MeSH Descriptor]
- estradiol preparation [SNOMED Notion]
Validated automatic mappings to NTBT
- Epimestrol [ICD-11 Extension code]
- Estradiol [SMS substance]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Estrogen Receptor [NCIt concept]
is_component_of_chemotherapy_regimen
- Estradiol Regimen [NCIt concept]

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