Triamcinolone Acetonide

Preferred Label : Triamcinolone Acetonide;

NCIt synonyms : 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione; ReadySharp Triamcinolone;

NCIt definition : The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.;

UNII : F446C597KA;

InChIKey : YNDXUCZADRHECN-JNQJZLCISA-N;

CAS number : 76-25-5;

Drug name : Aristocort A; Kenalog; AllerNaze; Nasacort;

Chemical formula : C24H31FO6;

NSC code : 21916;

Codes from synonyms : 00733;

Details

Origin ID

C48027;

UMLS CUI

C0040866;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Triamcinolone acetonide [LOINC component]
- Triamcinolone acetonide (substance) [SNOMED CT concept]
- triamcinolone acetonide [Substance BNPC]
- triamcinolone acetonide [MeSH concept]
- triamcinolone acetonide [MeSH Descriptor]
- triamcinolone acetonide [SNOMED Notion]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Intralesional Triamcinolone Regimen [NCIt concept]

Keyword's position in hierarchy(ies) :

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