Desoximetasone

Preferred Label : Desoximetasone;

NCIt synonyms : Topsilon; 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione;

NCIt definition : A synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity. Desoximetasone activates specific intracellular receptors, which bind to distinct sites on DNA to modify gene transcription. This results in an induction of the synthesis of anti-inflammatory proteins and suppression of the synthesis of inflammatory mediators. This leads to an overall reduction in chronic inflammation and autoimmune reactions. Desoximetasone is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.;

UNII : 4E07GXB7AU;

InChIKey : VWVSBHGCDBMOOT-IIEHVVJPSA-N;

CAS number : 382-67-2;

Drug name : Topicort LP; Topicort;

Chemical formula : C22H29FO4;

NSC code : 10482;

ChEBI ID : CHEBI:691037;

Details

Origin ID

C47477;

UMLS CUI

C0011707;

Currated CISMeF NLP mapping
- Desoximetasone [ICD-11 Extension code]
- Desoximetasone (substance) [SNOMED CT concept]
- desoximetasone [ATC Code]
- desoximetasone [Substance BNPC]
- desoximetasone [MeSH Descriptor]
- desoximetasone [MeSH concept]
- desoximetasone [SNOMED Notion]
See also inter- (CISMeF)
- Product containing desoximetasone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Desoximetasone [ICD-11 Extension code]
- Desoximetasone (substance) [SNOMED CT concept]
- Product containing desoximetasone (medicinal product) [SNOMED CT concept]
- desoximetasone [ATC Code]
- desoximetasone [ATC Code]
- desoximetasone [Substance BNPC]
- desoximetasone [MeSH concept]
- desoximetasone [MeSH Descriptor]
- desoximetasone [SNOMED Notion]
Validated automatic mappings to BTNT
- desoximetasone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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