" /> Flutamide - CISMeF





Preferred Label : Flutamide;

NCIt synonyms : 4'-Nitro-3'-trifluoromethylisobutyranilide; Flucinom; Alpha,alpha,alpha-trifluoro-2-methy-4'-nitro-m-propionotoluidide; Niftolide; Flugerel; FLUT; 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; Eulexin; Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-;

NCIt related terms : Sch 13521;

NCIt definition : A toluidine derivative and a nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that is a type of antiandrogen.;

UNII : 76W6J0943E;

InChIKey : MKXKFYHWDHIYRV-UHFFFAOYSA-N;

CAS number : 13311-84-7;

Drug name : Eulexine; Fugerel; Profamid; Fluta-Gry; Prostica; Fluken; Prostacur; Drogenil; Oncosal; Flutamin; Prostadirex; Flutan; Flutacan; Flutamex; Grisetin; Flutaplex; Euflex; Testotard; Chimax; Apimid; Prostogenat; Flucinome; Flulem; Flutabene; Tecnoflut; Tafenil; Cytomid; Cebatrol;

Molecule name : SCH 13521;

Chemical formula : C11H11F3N2O3;

NSC code : 147834; 215876;

ChEBI ID : CHEBI:5132;

Codes from synonyms : CDR0000045264; NSC0215876; 01895; 227;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
11/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.