Negative Regulation of Receptor Activation

Preferred Label : Negative Regulation of Receptor Activation;

NCIt synonyms : Receptor Inactivation; Receptor Inhibition;

NCIt definition : Any intercellular signaling process that reduces the frequency or extent of binding of a cognate ligand to an intracellular or transmembrane receptor to initiate an intracellular response. Receptor inhibition is involved in numerous processes, including metabolism, immune response, sexual development, nervous system function, and regulation of circadian rhythms, mood and behavior.;

Details

Origin ID

C40703;

UMLS CUI

C1514761;

Automatic exact mappings (from CISMeF team)
- negative regulation of signaling receptor activity [GO term]
Semantic type(s)
- Cell Function [UMLS semantic type]
biological_process_is_part_of_process
- Intercellular Communication Process [NCIt concept]
is_mechanism_of_action_of_chemical_or_drug
- AR Antagonist BMS-641988 [NCIt concept]
- Androgen Receptor Antagonist TRC253 [NCIt concept]
- Darolutamide [NCIt concept]
- Flutamide [NCIt concept]
- Gefitinib [NCIt concept]
- Masofaniten [NCIt concept]
- Monoclonal Antibody A27.15 [NCIt concept]
- Ralaniten Acetate [NCIt concept]
- Semaxanib [NCIt concept]
- Shark Cartilage Extract AE-941 [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- MoAb Bombesin (DTPA) [NCIt concept]
- MoAb Bombesin (ITC-D) [NCIt concept]
- Monoclonal Antibody E2.3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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