MoAb Bombesin (ITC-D)

Preferred Label : MoAb Bombesin (ITC-D);

NCIt synonyms : Monoclonal Antibody Bombesin-ITC-D; MOAB BOMBESIN ITC-D;

NCIt definition : A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows the antibody to be labeled with a metal species. Levels of the neurohormone bombesin, also known as gastrin releasing peptide (GRP), are elevated in lung and thyroid cancers, where the substance acts as an autocrine growth factor. (NCI04);

Details

Origin ID

C29213;

UMLS CUI

C1513439;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_gene_product
- Bombesin Receptor Subtype-3 [NCIt concept]
- Gastrin-Releasing Peptide [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Antigen Targeting [NCIt concept]
- Negative Regulation of Receptor Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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