NCIt definition : A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant
and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing
polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity
is not understood; however, carbamazepine is commonly used to treat pain associated
with trigeminal neuralgia.;