CYP3A4 Gene - CISMeF

Preferred Label : CYP3A4 Gene;

NCIt synonyms : Cytochrome P450 Family 3 Subfamily A Member 4 Gene; CYP3A4;

CISMeF acronym : CYP3A4;

NCIt definition : This gene plays an role in the metabolism of numerous clinically-relevant drugs. It is also involved in the oxidation of both endogenous substrates and xenobiotics.;

Details

Origin ID

C24328;

UMLS CUI

C1176140;

Automatic exact mappings (from CISMeF team)
- CYP3A4 gene [LOINC component]
- Cytochrome p450 CYP3A4 enzyme (substance) [SNOMED CT concept]
- Cytochrome p450, subfamily iiia, polypeptide 4 [OMIM gene]
- cytochrome P450 family 3 subfamily A member 4 [ORDO Gene]
- cytochrome p-450 cyp3a [MeSH Descriptor]
- taurochenodeoxycholate 6alpha-hydroxylase activity [GO term]
HGNC gene
- cytochrome P450 family 3 subfamily A member 4 [HGNC gene]
OMIM relation
- Cytochrome p450, subfamily iiia, polypeptide 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- CYP3A4 gene [LOINC component]
- Cytochrome p450, subfamily iiia, polypeptide 4 [OMIM gene]
- cytochrome P450 family 3 subfamily A member 4 [HGNC gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Reference Gene Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytochrome P450 3A4 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Carcinogen Metabolism [NCIt concept]
- Detoxification [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Iron Chelation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]
genetic_biomarker_related_to
- CYP3A4 Polymorphism Positive [NCIt concept]

Keyword's position in hierarchy(ies) :

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