Preferred Label : Deflazacort;
NCIt synonyms : 11Beta,21-Dihydroxy-2'-Methyl-5'Beta-H-Pregna-1,4-Dieno(17,16-D)Oxazole-3,20-Dione
21-Acetate; 5'H-Pregna-1,4-Dieno(17,16-d)Oxazole-3,20-Dione, 21-(Acetyloxy)-11-Hydroxy-2'-Methyl-,
(11Beta,16Beta)-;
NCIt definition : A synthetic glucocorticoid prodrug, with anti-inflammatory and immunomodulating properties.
Upon administration, the active metabolite of deflazacort, 21-desacetyl deflazacort,
binds to and activates tissue glucocorticoid receptors. This results in the inhibition
of specific leukocyte functions and the inhibition of proinflammatory cytokine production.;
UNII : KR5YZ6AE4B;
InChIKey : FBHSPRKOSMHSIF-GRMWVWQJSA-N;
CAS number : 14484-47-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 14484-47-0
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G-SRS /a ;
Drug name : Emflaza;
Molecule name : MDL 458;
Chemical formula : C25H31NO6;
Origin ID : C87230;
UMLS CUI : C0057258;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset
