NCIt related terms : CP4071; (3beta,5beta)-3-[(O-2,6-Dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide;
NCIt definition : A lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium
ATPase, leading to increased intracellular sodium and calcium levels and decreased
intracellular potassium levels. In studies increased intracellular calcium precedes
cell death and decreased intracellular potassium increase caspase activation and DNA
fragmentation, causing apoptosis and inhibition of cancer cell growth. (NCI);
Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for cancer.;