" /> Triazolam - CISMeF





Preferred Label : Triazolam;

NCIt synonyms : 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine; Clorazolam;

NCIt definition : A triazolobenzodiazepinederivative with sedative-hypnotic property. Triazolam interacts directly with a specific site on the gamma-aminobutyric acid (GABA)-A-chloride-ionophore receptor complex located on the neuronal membrane. Binding causes allosteric modification of the receptor and modulation of its affinity for the inhibitory neurotransmitter GABA. This results in enhancement of synaptic actions of GABA and includes an increase in the frequency of chloride channel openings, increased chloride ion conductance, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability.;

UNII : 1HM943223R;

InChIKey : JOFWLTCLBGQGBO-UHFFFAOYSA-N;

CAS number : 28911-01-5;

Drug name : Songar; Halcion; Novidorm;

Molecule name : U 33030; U-33,030;

Chemical formula : C17H12Cl2N4;

ChEBI ID : CHEBI:9674;

Détails


Position du mot-clé dans l'(les) arborescence(s) : arborescence

Vous pouvez consulter :


Nous contacter.
31/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.