" /> Hydrocortisone Hemisuccinate - CISMeF





Preferred Label : Hydrocortisone Hemisuccinate;

NCIt definition : The synthetic hemisuccinate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes.;

UNII : LIU00Z1Z84;

InChIKey : AFLWPAGYTPJSEY-CODXZCKSSA-N;

CAS number : 83784-20-7;

Chemical formula : C25H34O8.H2O;

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10/05/2025


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