" /> Clarithromycin - CISMeF





Preferred Label : Clarithromycin;

NCIt synonyms : Abbott-56268; 6-O-Methylerythromycin;

NCIt definition : A semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Clarithromycin has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04);

Alternative definition : NCI-GLOSS: An antibiotic drug used to treat infection. It belongs to the family of drugs called macrolides.;

UNII : H1250JIK0A;

InChIKey : AGOYDEPGAOXOCK-KCBOHYOISA-N;

CAS number : 81103-11-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 81103-11-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Biaxin;

Chemical formula : C38H69NO13;

NSC code : 643733;

ChEBI ID : CHEBI:3732;

Codes from synonyms : NSC0643733; CDR0000045449; 09601; 108;

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11/05/2024


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