Beclomethasone Dipropionate

Preferred Label : Beclomethasone Dipropionate;

NCIt synonyms : (11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione Dipropionate; Beclomethasone;

NCIt definition : The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.;

UNII : 5B307S63B2;

InChIKey : KUVIULQEHSCUHY-XYWKZLDCSA-N;

CAS number : 5534-09-8;

Drug name : Vancenase; Beconase; Beclovent; Qvar; Vanceril; QNASL;

Molecule name : SCH-18020W;

Chemical formula : C28H37ClO7;

ChEBI ID : CHEBI:3002;

Codes from synonyms : 09003;

Details

Origin ID

C299;

UMLS CUI

C0004906;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Beclometasone (substance) [SNOMED CT concept]
- Beclomethasone [ICD-11 Extension code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Glucocorticoid Receptor [NCIt concept]
is_component_of_chemotherapy_regimen
- Beclomethasone/Methylprednisolone [NCIt concept]
- Beclomethasone/Prednisone [NCIt concept]

Keyword's position in hierarchy(ies) :

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