NCIt related terms : 17,21-Dihydroxypregn-4-ene-3,11,20-trione;
NCIt definition : A corticosteroid with potent glucocorticoid activity. Therapeutic cortisone is the
inactive precursor molecule of the active hormone cortisol, which is the hydroxylation
product of cortisone by 11-beta-steroid dehydrogenase. Cortisol increases blood pressure
and blood sugar levels, and suppresses the immune system, therefore cortisone is used
to treat allergies or inflammation.;