Flurandrenolide

Preferred Label : Flurandrenolide;

NCIt synonyms : Fludroxycortide; 6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone;

NCIt definition : A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.;

UNII : 8EUL29XUQT;

InChIKey : POPFMWWJOGLOIF-XWCQMRHXSA-N;

CAS number : 1524-88-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1524-88-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Cordran;

Chemical formula : C24H33FO6;

Details

Origin ID

C47537;

UMLS CUI

C0016374;

Currated CISMeF NLP mapping
- Fludroxycortide [ICD-11 Extension code]
- Fludroxycortide (substance) [SNOMED CT concept]
- flurandrenolide, nos [SNOMED Notion]
- flurandrenolone [MeSH concept]
- flurandrenolone [MeSH Descriptor]
- flurandrenolone [Substance BNPC]
See also inter- (CISMeF)
- Flurandrenolide [ICD-11 Extension code]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fludroxycortide [ICD-11 Extension code]
- Fludroxycortide (substance) [SNOMED CT concept]
- Product containing fludroxycortide (medicinal product) [SNOMED CT concept]
- fludroxycortide [ATC Code]
- flurandrenolide, nos [SNOMED Notion]
- flurandrenolone [Substance BNPC]
- flurandrenolone [MeSH concept]
- flurandrenolone [MeSH Descriptor]
- flurandrenolone preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- fludroxycortide [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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