NCIt definition : A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic,
and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid
(GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating
the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain
omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel
receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.;