Zaleplon - CISMeF

Preferred Label : Zaleplon;

NCIt definition : A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.;

UNII : S62U433RMH;

InChIKey : HUNXMJYCHXQEGX-UHFFFAOYSA-N;

CAS number : 151319-34-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 151319-34-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Sonata;

Chemical formula : C17H15N5O;

ChEBI ID : CHEBI:10102;

Details

Origin ID

C29551;

UMLS CUI

C0251504;

Automatic exact mappings (from CISMeF team)
- zaleplon [ICD-11 Extension code]
See also inter- (CISMeF)
- Product containing zaleplon (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing zaleplon (medicinal product) [SNOMED CT concept]
- Zaleplon [LOINC component]
- Zaleplon (substance) [SNOMED CT concept]
- zaleplon [ATC Code]
- zaleplon [MeSH Supplementary Concept]
- zaleplon [MeSH concept]
Validated automatic mappings to BTNT
- zaleplon [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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