Preferred Label : Itraconazole;
NCIt synonyms : Oriconazole; ( -)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup
2)-1,2,4-triazolin-5-one;
NCIt definition : A synthetic triazole agent with antimycotic properties. Formulated for both topical
and systemic use, itraconazole preferentially inhibits fungal cytochrome P450 enzymes,
resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity
profile, this agent can be used for long-term maintenance treatment of chronic fungal
infections. (NCI04);
Alternative definition : NCI-GLOSS: A drug used to prevent or treat fungal infections. It belongs to the family
of drugs called antifungal agents.;
UNII : 304NUG5GF4;
InChIKey : VHVPQPYKVGDNFY-ZPGVKDDISA-N;
CAS number : 84625-61-6;
Drug name : Sporanox; Lozanoc;
Molecule name : R 51,211;
Chemical formula : C35H38Cl2N8O4;
ChEBI ID : CHEBI:6076;
Codes from synonyms : CDR0000045161; 286;
Origin ID : C1138;
UMLS CUI : C0064113;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset
