itraconazole - CISMeF

Preferred Label : itraconazole;

MeSH definition : A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.;

CISMeF synonym : janssen brand of itraconazole; itraconazole janssen brand; Janssen-Cilag brand of itraconazole; janssen cilag brand of itraconazole;

MeSH hyponym : R-51211; sporanox; orungal; R 51211; R51211;

MeSH CAS label : 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-;

MeSH Related Number : 84625-61-6 (Itraconazole);

Registry Number MeSH : 84625-61-6;

Wikipedia link : https://en.wikipedia.org/wiki/Itraconazole;

Is substance : O;

UNII : 304NUG5GF4;

InChIKey : VHVPQPYKVGDNFY-ZPGVKDDISA-N;

Details

Origin ID

D017964;

UMLS CUI

C0064113;

ATC code(s)
- itraconazole [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Itraconazole adverse reaction (disorder) [SNOMED CT concept]
- Itraconazole measurement (procedure) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Itraconazole [ICD-11 Extension code]
- Itraconazole [LOINC component]
- Itraconazole [ICHI extension code]
- Itraconazole [SMS substance]
- Itraconazole [NCIt concept]
- Itraconazole (substance) [SNOMED CT concept]
- itraconazole [SNOMED Notion]
Pharmacological action(s)
- 14-alpha demethylase inhibitors [MeSH Descriptor]
- Cytochrome P-450 CYP3A Inhibitors [MeSH Descriptor]
- antifungal agents [MeSH Descriptor]
Record concept(s)
- R-51211 [MeSH concept]
- itraconazole [MeSH concept]
- orungal [MeSH concept]
- sporanox [MeSH concept]
Related MeSH Supplementary Concept(s)
- cyclodextrin itraconazole [MeSH Supplementary Concept]
- hydroxyitraconazole [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing itraconazole (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Itraconazole [ICD-11 Extension code]
- Itraconazole [NCIt concept]
- Itraconazole [LOINC component]
- Itraconazole (substance) [SNOMED CT concept]
- Product containing itraconazole (medicinal product) [SNOMED CT concept]
- itraconazole [ATC Code]
- itraconazole [SNOMED Notion]
Validated automatic mappings to BTNT
- itraconazole [ATC Code]

Keyword's position in hierarchy(ies) :

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