Venlafaxine - CISMeF

Preferred Label : Venlafaxine;

NCIt definition : A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04);

Alternative definition : NCI-GLOSS: An antidepressant drug that is being evaluated for the treatment of hot flashes in women who have breast cancer.;

UNII : GRZ5RCB1QG;

InChIKey : PNVNVHUZROJLTJ-UHFFFAOYSA-N;

CAS number : 93413-69-5;

Chemical formula : C17H27NO2;

ChEBI ID : CHEBI:9943;

Codes from synonyms : CDR0000046117;

Details

Origin ID

C1278;

UMLS CUI

C0078569;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing venlafaxine (medicinal product) [SNOMED CT concept]
- Venlafaxine [ICD-11 Extension code]
- Venlafaxine [LOINC component]
- Venlafaxine (substance) [SNOMED CT concept]
- venlafaxine [ATC Code]
- venlafaxine [Substance BNPC]
- venlafaxine [MeSH concept]
Validated automatic mappings to BTNT
- Venlafaxine Hydrochloride [MeSH Descriptor]
- Venlafaxine hydrochloride (substance) [SNOMED CT concept]
- venlafaxine [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Venlafaxine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Venlafaxine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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